cTnI——The Gold Standard in AMI Diagnosis​
30

/Sep 2021

What is cTnI?

Troponin (Tn) is a complex of three regulatory proteins (C, I, T) that is integral to muscle contraction in skeletal muscle and cardiac muscle, but not smooth muscle. However, TnT and TnI in cardiac muscle are presented by forms different from those in skeletal muscles.


Distribution of cTnI during AMI

When AMI and myocardial cell damage occurs: The free cTnI in cardiac muscle is released to blood circulation first. As myocardial cell damage continues, cTn complex is released to blood as well and is degraded to cTnI, cTnT, TnC.


When to Arise

Detectable levels of cTnI are seen within 4-6 h following an AMI, which normally reach a peak within 12-24 h and remain elevated for 6-10 days.


Clinical Application

1. Specific and sensitive biomarker of cardiac injury.

2. The Gold Standard in AMI diagnosis.

3. The measurement of cTnI in blood is recommended by ESC, ACC and AHA as a standard biomarker for the diagnosis of AMI.


Detection of cTnI can be applied to

1. Diagnosis of acute coronary syndrome (ACS), especially immediate diagnosis and risk stratification of AMI.

2. Observation of treatment effect of AMI.

3. Auxiliary diagnosis of acute myocarditis, unstable angina, and other myocardial damage caused by chemotherapy, radiotherapy, intoxication, etc.


Getein cTnI Test Kit


cTnI Test Kit (Immunofluorescence Assay)

Matched with Getein1100


Getein 1100 Immunofluorescence Quantitative Analyzer


Getein1100 Immunofluorescence Assay Analyzer

-  Portable Design

-  Multiplex Test Items

-  Easy to Use

-  Reliable Performance

-  LIS and HIS Connectivity


cTnI Test Kit (Colloidal Gold)
Matched with Getein1100


FIA8000 Quantitative Immunoassay Analyzer

-Portable Design

-Multiplex Test Items

-Easy to Use

-Reliable Performance

-LIS and HIS Connectivity


hs-cTnI Test Kit (Immunofluorescence Assay)

Matched with Getein1600


Getein 1600 Immunofluorescence Quantitative Analyzer

-  Android System

-  High Throughput

-  On-Site Testing

-  Reliable Performance

-  LIS and HIS Connectivity

-  WIFI/4G Data Transmission


Reagent Information

Matched with Getein1100


Operation


Matched with Getein1100


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